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Nutritional status in patients with liver cirrhosis

AIM OF THE STUDY: To evaluate the nutritional status in patients with liver cirrhosis, depending on the stage of the disease. Fatty body mass, lean body mass and fluid content were determined, as well as basal metabolic rate. MATERIAL AND METHODS: The study included 56 patients with liver cirrhosis,...

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Autores principales: Łapiński, Tadeusz Wojciech, Łapińska, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431088/
https://www.ncbi.nlm.nih.gov/pubmed/30915404
http://dx.doi.org/10.5114/ceh.2019.83154
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author Łapiński, Tadeusz Wojciech
Łapińska, Magda
author_facet Łapiński, Tadeusz Wojciech
Łapińska, Magda
author_sort Łapiński, Tadeusz Wojciech
collection PubMed
description AIM OF THE STUDY: To evaluate the nutritional status in patients with liver cirrhosis, depending on the stage of the disease. Fatty body mass, lean body mass and fluid content were determined, as well as basal metabolic rate. MATERIAL AND METHODS: The study included 56 patients with liver cirrhosis, aged 54 ±12 years. Nutritional status was determined with the BMI and albumin serum concentration. Fatty body mass, lean body mass and fluid content, as well as basal metabolic rate, were estimated by bioelectrical impedance, using a MALTRON 907 analyzer. RESULTS: Based on albumin concentration, malnutrition was diagnosed in over 80% of patients, usually (100%) in patients with liver cirrhosis belonging to Child-Pugh class C. In all patients, high energy demand was found in relation to basal metabolic rate. Average fatty body mass was comparable in all patients and ranged from 24 to 30%. Fluid content in the tissues was comparable in all evaluated groups and did not correlate with accompanying ascites. Fluid excess was found in 25% of Child-Pugh class A patients, in 59% of class B patients and in 60% of class C patients. CONCLUSIONS: Malnutrition is present in over 80% of patients with liver cirrhosis, and its frequency correlates with the stage of liver insufficiency. Patients with liver cirrhosis show high energy demand for basal metabolic processes. Fluid excess is mainly found in patients with more severe liver injury, but it does not correlate directly with ascites.
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spelling pubmed-64310882019-03-26 Nutritional status in patients with liver cirrhosis Łapiński, Tadeusz Wojciech Łapińska, Magda Clin Exp Hepatol Original Paper AIM OF THE STUDY: To evaluate the nutritional status in patients with liver cirrhosis, depending on the stage of the disease. Fatty body mass, lean body mass and fluid content were determined, as well as basal metabolic rate. MATERIAL AND METHODS: The study included 56 patients with liver cirrhosis, aged 54 ±12 years. Nutritional status was determined with the BMI and albumin serum concentration. Fatty body mass, lean body mass and fluid content, as well as basal metabolic rate, were estimated by bioelectrical impedance, using a MALTRON 907 analyzer. RESULTS: Based on albumin concentration, malnutrition was diagnosed in over 80% of patients, usually (100%) in patients with liver cirrhosis belonging to Child-Pugh class C. In all patients, high energy demand was found in relation to basal metabolic rate. Average fatty body mass was comparable in all patients and ranged from 24 to 30%. Fluid content in the tissues was comparable in all evaluated groups and did not correlate with accompanying ascites. Fluid excess was found in 25% of Child-Pugh class A patients, in 59% of class B patients and in 60% of class C patients. CONCLUSIONS: Malnutrition is present in over 80% of patients with liver cirrhosis, and its frequency correlates with the stage of liver insufficiency. Patients with liver cirrhosis show high energy demand for basal metabolic processes. Fluid excess is mainly found in patients with more severe liver injury, but it does not correlate directly with ascites. Termedia Publishing House 2019-02-20 2019-03 /pmc/articles/PMC6431088/ /pubmed/30915404 http://dx.doi.org/10.5114/ceh.2019.83154 Text en Copyright: © 2019 Clinical and Experimental Hepatology http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Łapiński, Tadeusz Wojciech
Łapińska, Magda
Nutritional status in patients with liver cirrhosis
title Nutritional status in patients with liver cirrhosis
title_full Nutritional status in patients with liver cirrhosis
title_fullStr Nutritional status in patients with liver cirrhosis
title_full_unstemmed Nutritional status in patients with liver cirrhosis
title_short Nutritional status in patients with liver cirrhosis
title_sort nutritional status in patients with liver cirrhosis
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431088/
https://www.ncbi.nlm.nih.gov/pubmed/30915404
http://dx.doi.org/10.5114/ceh.2019.83154
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