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Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code

PURPOSE: Dosimetric characterization of a new 32P brachytherapy source was studied and the validity of the FLUKA code to reproduce the dosimetric parameters in a water phantom was evaluated. In addition, dose rate distributions around the 32P source sheathed by a catheter and unsheathed source were...

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Autores principales: Rajabi, Razieh, Taherparvar, Payvand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431097/
https://www.ncbi.nlm.nih.gov/pubmed/30911314
http://dx.doi.org/10.5114/jcb.2019.83002
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author Rajabi, Razieh
Taherparvar, Payvand
author_facet Rajabi, Razieh
Taherparvar, Payvand
author_sort Rajabi, Razieh
collection PubMed
description PURPOSE: Dosimetric characterization of a new 32P brachytherapy source was studied and the validity of the FLUKA code to reproduce the dosimetric parameters in a water phantom was evaluated. In addition, dose rate distributions around the 32P source sheathed by a catheter and unsheathed source were investigated in different tissue phantoms. MATERIAL AND METHODS: The new 32P source was modeled using FLUKA Monte Carlo code. According to the AAPM TG-60 recommendations, reference of absorbed dose rate, radial dose function, anisotropy function, and an away-along table for quality assurance purposes inside water phantom were calculated. Moreover, the results of the radial dose function and dose rate were obtained for the sheathed source and unsheathed sources at radial distances in different tissue phantoms: liver, fat tissue, 9-component soft tissue, and 4-component soft tissue. RESULTS: The calculated dosimetric parameters of the new 32P source by FLUKA code in water phantom agreed well with that of the GEANT4 calculation. The 2D away-along dose results were similar to the GEANT4 simulation for distances less than 0.25 cm, small differences were apparent at long distances from the source. Dose rate evaluation for the sheathed source shows that the presence of a catheter increases the dose values up to 2.11% in comparison with the unsheathed source in water phantom. Our results show that the radial dose function calculated in water, as generalized by AAPM TG-60, differed in tissue, especially at large distances from the source. CONCLUSIONS: This work fully characterizes dosimetric parameters of the sheathed and unsheathed new 32P brachytherapy sources in water and different tissue phantoms by using FLUKA code. The results demonstrate that the dose distribution in water differed from the calculated ones in tissue phantoms due to the densities and atomic composition for tissues that are not taken account by the TG-60 formalism.
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spelling pubmed-64310972019-03-25 Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code Rajabi, Razieh Taherparvar, Payvand J Contemp Brachytherapy Original Paper PURPOSE: Dosimetric characterization of a new 32P brachytherapy source was studied and the validity of the FLUKA code to reproduce the dosimetric parameters in a water phantom was evaluated. In addition, dose rate distributions around the 32P source sheathed by a catheter and unsheathed source were investigated in different tissue phantoms. MATERIAL AND METHODS: The new 32P source was modeled using FLUKA Monte Carlo code. According to the AAPM TG-60 recommendations, reference of absorbed dose rate, radial dose function, anisotropy function, and an away-along table for quality assurance purposes inside water phantom were calculated. Moreover, the results of the radial dose function and dose rate were obtained for the sheathed source and unsheathed sources at radial distances in different tissue phantoms: liver, fat tissue, 9-component soft tissue, and 4-component soft tissue. RESULTS: The calculated dosimetric parameters of the new 32P source by FLUKA code in water phantom agreed well with that of the GEANT4 calculation. The 2D away-along dose results were similar to the GEANT4 simulation for distances less than 0.25 cm, small differences were apparent at long distances from the source. Dose rate evaluation for the sheathed source shows that the presence of a catheter increases the dose values up to 2.11% in comparison with the unsheathed source in water phantom. Our results show that the radial dose function calculated in water, as generalized by AAPM TG-60, differed in tissue, especially at large distances from the source. CONCLUSIONS: This work fully characterizes dosimetric parameters of the sheathed and unsheathed new 32P brachytherapy sources in water and different tissue phantoms by using FLUKA code. The results demonstrate that the dose distribution in water differed from the calculated ones in tissue phantoms due to the densities and atomic composition for tissues that are not taken account by the TG-60 formalism. Termedia Publishing House 2019-02-28 2019-02 /pmc/articles/PMC6431097/ /pubmed/30911314 http://dx.doi.org/10.5114/jcb.2019.83002 Text en Copyright: © 2019 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Rajabi, Razieh
Taherparvar, Payvand
Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code
title Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code
title_full Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code
title_fullStr Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code
title_full_unstemmed Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code
title_short Monte Carlo dosimetry for a new (32)P brachytherapy source using FLUKA code
title_sort monte carlo dosimetry for a new (32)p brachytherapy source using fluka code
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431097/
https://www.ncbi.nlm.nih.gov/pubmed/30911314
http://dx.doi.org/10.5114/jcb.2019.83002
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