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Mukonal Inhibits Cell Proliferation, Alters Mitochondrial Membrane Potential and Induces Apoptosis and Autophagy in Human CNE1 Nasopharyngeal Carcinoma Cells

BACKGROUND: Nasopharyngeal carcinoma results in high patient morbidity and mortality, due to early metastasis, and toxicity due to chemotherapy. Mukonal is plant-derived carbazole alkaloid that has been used in traditional Chinese medicine to treat several types of cancer. This study aimed to invest...

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Detalles Bibliográficos
Autores principales: Guo, Yingyuan, Hao, Yanru, Guan, Guofang, Ma, Shuaishuai, Zhu, Zhiling, Guo, Fang, Bai, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431110/
https://www.ncbi.nlm.nih.gov/pubmed/30877718
http://dx.doi.org/10.12659/MSM.913915