The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine

A Chinese scientist, Jiankui He, and his creation of the world's first genetically altered baby made headlines recently. As a newly developed gene‐editing technique, the CRISPR/Cas system should not be applied to human beings for reproductive purposes until it has been extensively tested. Howev...

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Detalles Bibliográficos
Autores principales: Yang, Yuyan, Huang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431121/
https://www.ncbi.nlm.nih.gov/pubmed/31016281
http://dx.doi.org/10.1002/ame2.12061
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author Yang, Yuyan
Huang, Yue
author_facet Yang, Yuyan
Huang, Yue
author_sort Yang, Yuyan
collection PubMed
description A Chinese scientist, Jiankui He, and his creation of the world's first genetically altered baby made headlines recently. As a newly developed gene‐editing technique, the CRISPR/Cas system should not be applied to human beings for reproductive purposes until it has been extensively tested. However, numerous experimental research studies in human somatic, germline cells, and even in embryos, have been conducted, which have shown CRISPR/Cas to be a useful tool for human genome editing and a potential therapeutic method for future clinical use.
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spelling pubmed-64311212019-04-23 The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine Yang, Yuyan Huang, Yue Animal Model Exp Med Commentary A Chinese scientist, Jiankui He, and his creation of the world's first genetically altered baby made headlines recently. As a newly developed gene‐editing technique, the CRISPR/Cas system should not be applied to human beings for reproductive purposes until it has been extensively tested. However, numerous experimental research studies in human somatic, germline cells, and even in embryos, have been conducted, which have shown CRISPR/Cas to be a useful tool for human genome editing and a potential therapeutic method for future clinical use. John Wiley and Sons Inc. 2019-03-13 /pmc/articles/PMC6431121/ /pubmed/31016281 http://dx.doi.org/10.1002/ame2.12061 Text en © 2019 The Authors. Animal Models and Experimental Medicine published by John Wiley & Sons Australia, Ltd on behalf of The Chinese Association for Laboratory Animal Sciences This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Commentary
Yang, Yuyan
Huang, Yue
The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine
title The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine
title_full The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine
title_fullStr The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine
title_full_unstemmed The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine
title_short The CRIPSR/Cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine
title_sort cripsr/cas gene‐editing system—an immature but useful toolkit for experimental and clinical medicine
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431121/
https://www.ncbi.nlm.nih.gov/pubmed/31016281
http://dx.doi.org/10.1002/ame2.12061
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