Genomic and molecular characterization of preterm birth

Preterm birth (PTB) complications are the leading cause of long-term morbidity and mortality in children. By using whole blood samples, we integrated whole-genome sequencing (WGS), RNA sequencing (RNA-seq), and DNA methylation data for 270 PTB and 521 control families. We analyzed this combined data...

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Detalles Bibliográficos
Autores principales: Knijnenburg, Theo A., Vockley, Joseph G., Chambwe, Nyasha, Gibbs, David L., Humphries, Crystal, Huddleston, Kathi C., Klein, Elisabeth, Kothiyal, Prachi, Tasseff, Ryan, Dhankani, Varsha, Bodian, Dale L., Wong, Wendy S. W., Glusman, Gustavo, Mauldin, Denise E., Miller, Michael, Slagel, Joseph, Elasady, Summer, Roach, Jared C., Kramer, Roger, Leinonen, Kalle, Linthorst, Jasper, Baveja, Rajiv, Baker, Robin, Solomon, Benjamin D., Eley, Greg, Iyer, Ramaswamy K., Maxwell, George L., Bernard, Brady, Shmulevich, Ilya, Hood, Leroy, Niederhuber, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431191/
https://www.ncbi.nlm.nih.gov/pubmed/30833390
http://dx.doi.org/10.1073/pnas.1716314116

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