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Female genital tuberculosis: a clinicopathological report of 13 cases

Female genital tuberculosis (FGTB) is a rare form of tuberculosis (TB) affecting women of reproductive age. The clinical presentation is often misleading. We retrospectively collected cases of female genital tuberculosis (FGTB) diagnosed from 2006 to 2016 at our pathology department. The mean age wa...

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Autores principales: Efared, Boubacar, Sidibé, Ibrahim S, Erregad, Fatimazahra, Hammas, Nawal, Chbani, Laila, El Fatemi, Hinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431246/
https://www.ncbi.nlm.nih.gov/pubmed/30937159
http://dx.doi.org/10.1093/jscr/rjz083
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author Efared, Boubacar
Sidibé, Ibrahim S
Erregad, Fatimazahra
Hammas, Nawal
Chbani, Laila
El Fatemi, Hinde
author_facet Efared, Boubacar
Sidibé, Ibrahim S
Erregad, Fatimazahra
Hammas, Nawal
Chbani, Laila
El Fatemi, Hinde
author_sort Efared, Boubacar
collection PubMed
description Female genital tuberculosis (FGTB) is a rare form of tuberculosis (TB) affecting women of reproductive age. The clinical presentation is often misleading. We retrospectively collected cases of female genital tuberculosis (FGTB) diagnosed from 2006 to 2016 at our pathology department. The mean age was 39.92 years (range of 18–74 years). Most patients had reproductive age, with 30.76% postmenopausal women. Seven cases (53.84%) were addressed for histopathological analysis for clinical malignant suspicion. The diagnosis was made on eight surgical specimens (61.53%). Nine patients (69.23%) had multifocal TB. The most involved genital organs were fallopian tubes (63.84%), followed by ovaries (46.15%), endometrium (38.46%) and the cervix (23.07%). The macroscopic aspects of all resected specimens did not show the classic appearance of caseous necrosis. We found that most patients with genital tuberculosis present with clinical suspicion of malignancy leading to aggressive surgical management.
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spelling pubmed-64312462019-04-01 Female genital tuberculosis: a clinicopathological report of 13 cases Efared, Boubacar Sidibé, Ibrahim S Erregad, Fatimazahra Hammas, Nawal Chbani, Laila El Fatemi, Hinde J Surg Case Rep Case Report Female genital tuberculosis (FGTB) is a rare form of tuberculosis (TB) affecting women of reproductive age. The clinical presentation is often misleading. We retrospectively collected cases of female genital tuberculosis (FGTB) diagnosed from 2006 to 2016 at our pathology department. The mean age was 39.92 years (range of 18–74 years). Most patients had reproductive age, with 30.76% postmenopausal women. Seven cases (53.84%) were addressed for histopathological analysis for clinical malignant suspicion. The diagnosis was made on eight surgical specimens (61.53%). Nine patients (69.23%) had multifocal TB. The most involved genital organs were fallopian tubes (63.84%), followed by ovaries (46.15%), endometrium (38.46%) and the cervix (23.07%). The macroscopic aspects of all resected specimens did not show the classic appearance of caseous necrosis. We found that most patients with genital tuberculosis present with clinical suspicion of malignancy leading to aggressive surgical management. Oxford University Press 2019-03-23 /pmc/articles/PMC6431246/ /pubmed/30937159 http://dx.doi.org/10.1093/jscr/rjz083 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2019. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Efared, Boubacar
Sidibé, Ibrahim S
Erregad, Fatimazahra
Hammas, Nawal
Chbani, Laila
El Fatemi, Hinde
Female genital tuberculosis: a clinicopathological report of 13 cases
title Female genital tuberculosis: a clinicopathological report of 13 cases
title_full Female genital tuberculosis: a clinicopathological report of 13 cases
title_fullStr Female genital tuberculosis: a clinicopathological report of 13 cases
title_full_unstemmed Female genital tuberculosis: a clinicopathological report of 13 cases
title_short Female genital tuberculosis: a clinicopathological report of 13 cases
title_sort female genital tuberculosis: a clinicopathological report of 13 cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431246/
https://www.ncbi.nlm.nih.gov/pubmed/30937159
http://dx.doi.org/10.1093/jscr/rjz083
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