Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy

We report the case of a 26-year-old woman with an eight-week history of painfully enlarged cervical lymph nodes, recurrent headache, and malaise. Her medical history was unremarkable. The physical examination showed multiple enlarged cervical lymph nodes. Laboratory examination was unremarkable, and...

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Detalles Bibliográficos
Autores principales: Gerwig, Ulrich, Weidmann, Rolf Guenter, Lindner, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431476/
https://www.ncbi.nlm.nih.gov/pubmed/30984430
http://dx.doi.org/10.1155/2019/6405687
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author Gerwig, Ulrich
Weidmann, Rolf Guenter
Lindner, Gregor
author_facet Gerwig, Ulrich
Weidmann, Rolf Guenter
Lindner, Gregor
author_sort Gerwig, Ulrich
collection PubMed
description We report the case of a 26-year-old woman with an eight-week history of painfully enlarged cervical lymph nodes, recurrent headache, and malaise. Her medical history was unremarkable. The physical examination showed multiple enlarged cervical lymph nodes. Laboratory examination was unremarkable, and magnetic resonance tomographic imaging showed multiple enlarged cervical lymph nodes with aspect of a lymphoma. Lymph node biopsy revealed Kikuchi-Fujimoto disease, histologically characterized by histiocytic necrotizing lymphadenitis. A therapeutic trial with nonsteroidal anti-inflammatory drugs (NSAID) showed no effect, so steroid therapy was started. Due to relapse of symptoms after steroid withdrawal the tapering regimen was prolonged for a total of seven months.
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spelling pubmed-64314762019-04-14 Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy Gerwig, Ulrich Weidmann, Rolf Guenter Lindner, Gregor Case Rep Emerg Med Case Report We report the case of a 26-year-old woman with an eight-week history of painfully enlarged cervical lymph nodes, recurrent headache, and malaise. Her medical history was unremarkable. The physical examination showed multiple enlarged cervical lymph nodes. Laboratory examination was unremarkable, and magnetic resonance tomographic imaging showed multiple enlarged cervical lymph nodes with aspect of a lymphoma. Lymph node biopsy revealed Kikuchi-Fujimoto disease, histologically characterized by histiocytic necrotizing lymphadenitis. A therapeutic trial with nonsteroidal anti-inflammatory drugs (NSAID) showed no effect, so steroid therapy was started. Due to relapse of symptoms after steroid withdrawal the tapering regimen was prolonged for a total of seven months. Hindawi 2019-03-07 /pmc/articles/PMC6431476/ /pubmed/30984430 http://dx.doi.org/10.1155/2019/6405687 Text en Copyright © 2019 Ulrich Gerwig et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gerwig, Ulrich
Weidmann, Rolf Guenter
Lindner, Gregor
Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy
title Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy
title_full Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy
title_fullStr Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy
title_full_unstemmed Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy
title_short Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy
title_sort relapsing kikuchi-fujimoto disease requiring prolonged steroid therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431476/
https://www.ncbi.nlm.nih.gov/pubmed/30984430
http://dx.doi.org/10.1155/2019/6405687
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AT lindnergregor relapsingkikuchifujimotodiseaserequiringprolongedsteroidtherapy

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