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Combined Activation of Guanylate Cyclase and Cyclic AMP in Lung Fibroblasts as a Novel Therapeutic Concept for Lung Fibrosis

Remodelling of the peripheral lung tissue and fibrotic foci are the main pathologies of idiopathic pulmonary fibrosis (IPF), a disease that is difficult to treat. TGF-β activation of peripheral lung fibroblasts is indicated as the major cause of tissue remodelling in IPF and is resulting in fibrobla...

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Detalles Bibliográficos
Autores principales: Lambers, Christopher, Boehm, Panja M., Karabacak, Yasemin, Samaha, Eslam, Benazzo, Alberto, Jaksch, Peter, Roth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431482/
https://www.ncbi.nlm.nih.gov/pubmed/30984775
http://dx.doi.org/10.1155/2019/1345402

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