Cargando…

Concise Review: Therapeutic Potential of the Mesenchymal Stem Cell Derived Secretome and Extracellular Vesicles for Radiation‐Induced Lung Injury: Progress and Hypotheses

Radiation‐induced lung injury (RILI) is a common complication in radiotherapy of thoracic tumors and limits the therapeutic dose of radiation that can be given to effectively control tumors. RILI develops through a complex pathological process, resulting in induction and activation of various cytoki...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Siguang, Liu, Cong, Ji, Hong‐Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Cell‐Based Drug Development, Screening, and Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431606/ https://www.ncbi.nlm.nih.gov/pubmed/30618085 http://dx.doi.org/10.1002/sctm.18-0038

Ejemplares similares

Mesenchymal Stem Cell-derived Extracellular Vesicles Prevent Experimental Bronchopulmonary Dysplasia Complicated By Pulmonary Hypertension
por: Sharma, Mayank, et al.
Publicado: (2022)

Brain‐derived neurotropic factor mediates neuroprotection of mesenchymal stem cell‐derived extracellular vesicles against severe intraventricular hemorrhage in newborn rats
por: Ahn, So Yoon, et al.
Publicado: (2020)

Lithium modulates miR‐1906 levels of mesenchymal stem cell‐derived extracellular vesicles contributing to poststroke neuroprotection by toll‐like receptor 4 regulation
por: Haupt, Matteo, et al.
Publicado: (2020)

Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A
por: Long, Yan, et al.
Publicado: (2016)

Mesenchymal Stromal Cells Modulate Corneal Alloimmunity via Secretion of Hepatocyte Growth Factor
por: Mittal, Sharad K., et al.
Publicado: (2019)

Site-Specific Integration of TRAIL in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer Therapy
por: Wang, Zujia, et al.
Publicado: (2022)

Treatment of chronic GvHD with mesenchymal stromal cells induces durable responses: A phase II study
por: Boberg, Erik, et al.
Publicado: (2020)

Mesenchymal Stromal Cells Suppress T-Cell-Mediated Delayed-Type Hypersensitivity via ALCAM-CD6 Interaction
por: Cho, WonKyung J, et al.
Publicado: (2023)

Cytokine Mixtures Mimicking the Local Milieu in Patients with Inflammatory Bowel Disease Impact Phenotype and Function of Mesenchymal Stromal Cells
por: Barnhoorn, Marieke C, et al.
Publicado: (2022)

Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae
por: Perlee, Desiree, et al.
Publicado: (2019)

Human Mesenchymal Stem Cells Impact Th17 and Th1 Responses Through a Prostaglandin E2 and Myeloid-Dependent Mechanism
por: Rozenberg, Ayal, et al.
Publicado: (2016)

A Phase I Study to Assess the Safety and Cancer‐Homing Ability of Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer
por: Schweizer, Michael T., et al.
Publicado: (2019)

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress
por: Thorne, Natasha, et al.
Publicado: (2016)

miR-145 Regulates Diabetes-Bone Marrow Stromal Cell-Induced Neurorestorative Effects in Diabetes Stroke Rats
por: Cui, Chengcheng, et al.
Publicado: (2016)

Phenotypic Drug Screening for Dysferlinopathy Using Patient‐Derived Induced Pluripotent Stem Cells
por: Kokubu, Yuko, et al.
Publicado: (2019)

Stromal cells from perinatal and adult sources modulate the inflammatory immune response in vitro by decreasing Th1 cell proliferation and cytokine secretion
por: Khoury, Oula, et al.
Publicado: (2019)

Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach
por: Drowley, Lauren, et al.
Publicado: (2019)

Chemotherapy‐Induced Neuropathy and Drug Discovery Platform Using Human Sensory Neurons Converted Directly from Adult Peripheral Blood
por: Vojnits, Kinga, et al.
Publicado: (2019)

Systemic multipotent adult progenitor cells protect the cerebellum after asphyxia in fetal sheep
por: Gussenhoven, Ruth, et al.
Publicado: (2020)

Drug screening platform using human induced pluripotent stem cell‐derived atrial cardiomyocytes and optical mapping
por: Gunawan, Marvin G., et al.
Publicado: (2020)

Rabbit neurospheres as a novel in vitro tool for studying neurodevelopmental effects induced by intrauterine growth restriction
por: Barenys, Marta, et al.
Publicado: (2020)

Allogeneic Cell Combination Therapy Ameliorates Chronic Kidney Disease-Induced Heart Failure with Preserved Ejection Fraction
por: Rieger, Angela C, et al.
Publicado: (2022)

Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina
por: Dorgau, Birthe, et al.
Publicado: (2022)

Otic Organoids Containing Spiral Ganglion Neuron-like Cells Derived from Human-induced Pluripotent Stem Cells as a Model of Drug-induced Neuropathy
por: Kurihara, Sho, et al.
Publicado: (2022)

Generation of Human Nociceptor-Enriched Sensory Neurons for the Study of Pain-Related Dysfunctions
por: Holzer, Anna-Katharina, et al.
Publicado: (2022)

Metabolic Maturation Increases Susceptibility to Hypoxia-induced Damage in Human iPSC-derived Cardiomyocytes
por: Peters, Marijn C, et al.
Publicado: (2022)

Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy
por: Golubeva, Diana, et al.
Publicado: (2023)

Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands
por: Conole, Daniel, et al.
Publicado: (2018)

Thorough QT/QTc Evaluation of the Cardiac Safety of Secnidazole at Therapeutic and Supratherapeutic Doses in Healthy Individuals
por: Darpo, Borje, et al.
Publicado: (2017)

Altered Functional Mitochondrial Protein Levels in Plasma Neuron-Derived Extracellular Vesicles of Patients With Gadolinium Deposition
por: Goetzl, Edward J., et al.
Publicado: (2022)

Wharton’s jelly mesenchymal stem cells: a concise review of their secretome and prospective clinical applications
por: Drobiova, Hana, et al.
Publicado: (2023)

Personalized medicine: Striding from genes to medicines
por: Nair, Sunita R.
Publicado: (2010)

Diabetes mellitus: Exploring the challenges in the drug development process
por: Vaz, Julius A., et al.
Publicado: (2012)

Evaluation of a Scenario in Which Estimates of Bioequivalence Are Biased and a Proposed Solution: t(last) (Common)
por: Fisher, Dennis, et al.
Publicado: (2015)

Effect of Study Design on Sample Size in Studies Intended to Evaluate Bioequivalence of Inhaled Short‐Acting β‐Agonist Formulations
por: Zeng, Yaohui, et al.
Publicado: (2017)

Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity
por: Ferber, Georg, et al.
Publicado: (2017)

The Cardiovascular Effects of a Meal: J‐T(peak) and T(peak)‐T(end) Assessment and Further Insights Into the Physiological Effects
por: Täubel, Jörg, et al.
Publicado: (2019)

Model‐Based Evaluation of Exenatide Effects on the QT Interval in Healthy Subjects Following Continuous IV Infusion
por: Cirincione, Brenda, et al.
Publicado: (2017)

Influence of Meals and Glycemic Changes on QT Interval Dynamics
por: Cirincione, Brenda, et al.
Publicado: (2017)

Epitope Mapping: The First Step in Developing Epitope-Based Vaccines
por: Gershoni, Jonathan M., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_d8hn6vh7ud8bldcttmca05gme4