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A Conceptual Framework for Studying and Investing in Precision Nutrition

Nutrients and food-derived bioactive molecules must transit complex metabolic pathways, and these pathways vary between people. Metabolic heterogeneity is caused by genetic variation, epigenetic variation, differences in microbiome composition and function, lifestyle differences and by variation in...

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Detalles Bibliográficos
Autor principal: Zeisel, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431609/
https://www.ncbi.nlm.nih.gov/pubmed/30936893
http://dx.doi.org/10.3389/fgene.2019.00200
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author Zeisel, Steven H.
author_facet Zeisel, Steven H.
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description Nutrients and food-derived bioactive molecules must transit complex metabolic pathways, and these pathways vary between people. Metabolic heterogeneity is caused by genetic variation, epigenetic variation, differences in microbiome composition and function, lifestyle differences and by variation in environmental exposures. This review discusses a number of these sources of metabolic heterogeneity and presents some of the research investments that will be needed to make applications of precision nutrition practical.
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spelling pubmed-64316092019-04-01 A Conceptual Framework for Studying and Investing in Precision Nutrition Zeisel, Steven H. Front Genet Genetics Nutrients and food-derived bioactive molecules must transit complex metabolic pathways, and these pathways vary between people. Metabolic heterogeneity is caused by genetic variation, epigenetic variation, differences in microbiome composition and function, lifestyle differences and by variation in environmental exposures. This review discusses a number of these sources of metabolic heterogeneity and presents some of the research investments that will be needed to make applications of precision nutrition practical. Frontiers Media S.A. 2019-03-18 /pmc/articles/PMC6431609/ /pubmed/30936893 http://dx.doi.org/10.3389/fgene.2019.00200 Text en Copyright © 2019 Zeisel. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Zeisel, Steven H.
A Conceptual Framework for Studying and Investing in Precision Nutrition
title A Conceptual Framework for Studying and Investing in Precision Nutrition
title_full A Conceptual Framework for Studying and Investing in Precision Nutrition
title_fullStr A Conceptual Framework for Studying and Investing in Precision Nutrition
title_full_unstemmed A Conceptual Framework for Studying and Investing in Precision Nutrition
title_short A Conceptual Framework for Studying and Investing in Precision Nutrition
title_sort conceptual framework for studying and investing in precision nutrition
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431609/
https://www.ncbi.nlm.nih.gov/pubmed/30936893
http://dx.doi.org/10.3389/fgene.2019.00200
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