Glucocorticoid Receptor-Deficient Foxp3(+) Regulatory T Cells Fail to Control Experimental Inflammatory Bowel Disease

Activation of the immune system increases systemic adrenal-derived glucocorticoid (GC) levels which downregulate the immune response as part of a negative feedback loop. While CD4(+) T cells are essential target cells affected by GC, it is not known whether these hormones exert their major effects o...

Descripción completa

Detalles Bibliográficos
Autores principales: Rocamora-Reverte, Lourdes, Tuzlak, Selma, von Raffay, Laura, Tisch, Marcel, Fiegl, Heidi, Drach, Mathias, Reichardt, Holger M., Villunger, Andreas, Tischner, Denise, Wiegers, G. Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431616/
https://www.ncbi.nlm.nih.gov/pubmed/30936873
http://dx.doi.org/10.3389/fimmu.2019.00472

Ejemplares similares

Ejemplares similares