A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy

Continued discoveries of negative regulators of inflammatory signaling provide detailed molecular insights into peripheral tolerance and anti-tumor immunity. Accumulating evidence indicates that peripheral tolerance is maintained at multiple levels of immune responses by negative regulators of proin...

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Detalles Bibliográficos
Autores principales: Guram, Kripa, Kim, Sangwoo S., Wu, Victoria, Sanders, P. Dominick, Patel, Sandip, Schoenberger, Stephen P., Cohen, Ezra E. W., Chen, Si-Yi, Sharabi, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431643/
https://www.ncbi.nlm.nih.gov/pubmed/30936880
http://dx.doi.org/10.3389/fimmu.2019.00491

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