Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8(+) T-Cell Activation

Inflammatory Bowel Disease (IBD) is a multi-factorial chronic inflammation of the gastrointestinal tract prognostically linked to CD8(+) T-cells, but little is known about their mechanism of activation during initiation of colitis. Here, Grb2-associated binding 2/3 adaptor protein double knockout mi...

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Detalles Bibliográficos
Autores principales: Wang, Zhengqi, Vaughan, Tamisha Y., Zhu, Wandi, Chen, Yuhong, Fu, Guoping, Medrzycki, Magdalena, Nishio, Hikaru, Bunting, Silvia T., Hankey-Giblin, Pamela A., Nusrat, Asma, Parkos, Charles A., Wang, Demin, Wen, Renren, Bunting, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431666/
https://www.ncbi.nlm.nih.gov/pubmed/30936879
http://dx.doi.org/10.3389/fimmu.2019.00486

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