Pharmacokinetic and Pharmacogenetic Factors Contributing to Platelet Function Recovery After Single Dose of Ticagrelor in Healthy Subjects

Objectives: This study aimed to elucidate the contribution of candidate single nucleotide polymorphisms (SNPs) related to pharmacokinetics on the recovery of platelet function after single dose of ticagrelor was orally administered to healthy Chinese subjects. Methods: The pharmacokinetic profiles o...

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Detalles Bibliográficos
Autores principales: Zhu, Qian, Zhong, Wanping, Wang, Xipei, Mai, Liping, He, Guodong, Chen, Jiyan, Tang, Lan, Liu, Shuwen, Lai, Weihua, Zhong, Shilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431676/
https://www.ncbi.nlm.nih.gov/pubmed/30936830
http://dx.doi.org/10.3389/fphar.2019.00209

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