Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens

Intracellular bacteria that live in host cell–derived vacuoles are significant causes of human disease. Parasitism of low-density lipoprotein (LDL) cholesterol is essential for many vacuole-adapted bacteria. Acid sphingomyelinase (ASM) influences LDL cholesterol egress from the lysosome. Using funct...

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Detalles Bibliográficos
Autores principales: Cockburn, Chelsea L, Green, Ryan S, Damle, Sheela R, Martin, Rebecca K, Ghahrai, Naomi N, Colonne, Punsiri M, Fullerton, Marissa S, Conrad, Daniel H, Chalfant, Charles E, Voth, Daniel E, Rucks, Elizabeth A, Gilk, Stacey D, Carlyon, Jason A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431796/
https://www.ncbi.nlm.nih.gov/pubmed/30902833
http://dx.doi.org/10.26508/lsa.201800292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431796/
https://www.ncbi.nlm.nih.gov/pubmed/30902833
http://dx.doi.org/10.26508/lsa.201800292

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