A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin

By taking advantage of the self-polymerization of dopamine on the surface of magnetic nanospheres in weak alkaline Tris-HCl buffer solution, a facile approach was established to fabricate core-shell magnetic molecularly imprinted nanospheres towards hypericin (Fe(3)O(4)@PDA/Hyp NSs), via a surface m...

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Autores principales: Cheng, Wenxia, Fan, Fengfeng, Zhang, Ying, Pei, Zhichao, Wang, Wenji, Pei, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431851/
https://www.ncbi.nlm.nih.gov/pubmed/30970815
http://dx.doi.org/10.3390/polym9040135
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author Cheng, Wenxia
Fan, Fengfeng
Zhang, Ying
Pei, Zhichao
Wang, Wenji
Pei, Yuxin
author_facet Cheng, Wenxia
Fan, Fengfeng
Zhang, Ying
Pei, Zhichao
Wang, Wenji
Pei, Yuxin
author_sort Cheng, Wenxia
collection PubMed
description By taking advantage of the self-polymerization of dopamine on the surface of magnetic nanospheres in weak alkaline Tris-HCl buffer solution, a facile approach was established to fabricate core-shell magnetic molecularly imprinted nanospheres towards hypericin (Fe(3)O(4)@PDA/Hyp NSs), via a surface molecular imprinting technique. The Fe(3)O(4)@PDA/Hyp NSs were characterized by FTIR, TEM, DLS, and BET methods, respectively. The reaction conditions for adsorption capacity and selectivity towards hypericin were optimized, and the Fe(3)O(4)@PDA/Hyp NSs synthesized under the optimized conditions showed a high adsorption capacity (Q = 18.28 mg/g) towards hypericin. The selectivity factors of Fe(3)O(4)@PDA/Hyp NSs were about 1.92 and 3.55 towards protohypericin and emodin, respectively. In addition, the approach established in this work showed good reproducibility for fabrication of Fe(3)O(4)@PDA/Hyp.
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spelling pubmed-64318512019-04-02 A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin Cheng, Wenxia Fan, Fengfeng Zhang, Ying Pei, Zhichao Wang, Wenji Pei, Yuxin Polymers (Basel) Article By taking advantage of the self-polymerization of dopamine on the surface of magnetic nanospheres in weak alkaline Tris-HCl buffer solution, a facile approach was established to fabricate core-shell magnetic molecularly imprinted nanospheres towards hypericin (Fe(3)O(4)@PDA/Hyp NSs), via a surface molecular imprinting technique. The Fe(3)O(4)@PDA/Hyp NSs were characterized by FTIR, TEM, DLS, and BET methods, respectively. The reaction conditions for adsorption capacity and selectivity towards hypericin were optimized, and the Fe(3)O(4)@PDA/Hyp NSs synthesized under the optimized conditions showed a high adsorption capacity (Q = 18.28 mg/g) towards hypericin. The selectivity factors of Fe(3)O(4)@PDA/Hyp NSs were about 1.92 and 3.55 towards protohypericin and emodin, respectively. In addition, the approach established in this work showed good reproducibility for fabrication of Fe(3)O(4)@PDA/Hyp. MDPI 2017-04-07 /pmc/articles/PMC6431851/ /pubmed/30970815 http://dx.doi.org/10.3390/polym9040135 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cheng, Wenxia
Fan, Fengfeng
Zhang, Ying
Pei, Zhichao
Wang, Wenji
Pei, Yuxin
A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin
title A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin
title_full A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin
title_fullStr A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin
title_full_unstemmed A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin
title_short A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin
title_sort facile approach for fabrication of core-shell magnetic molecularly imprinted nanospheres towards hypericin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431851/
https://www.ncbi.nlm.nih.gov/pubmed/30970815
http://dx.doi.org/10.3390/polym9040135
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