System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers

Helical polymer bundles are an important fixture in biomolecular systems. The particular structural geometry of helix bundles is dependent on many factors including the length of the polymer chain. In this study, we performed Monte Carlo simulations of a coarse-grained model for helical polymers to...

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Detalles Bibliográficos
Autores principales: Williams, Matthew J., Bachmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431926/
https://www.ncbi.nlm.nih.gov/pubmed/30974521
http://dx.doi.org/10.3390/polym8070245
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author Williams, Matthew J.
Bachmann, Michael
author_facet Williams, Matthew J.
Bachmann, Michael
author_sort Williams, Matthew J.
collection PubMed
description Helical polymer bundles are an important fixture in biomolecular systems. The particular structural geometry of helix bundles is dependent on many factors including the length of the polymer chain. In this study, we performed Monte Carlo simulations of a coarse-grained model for helical polymers to determine the influence of polymer length on tertiary structure formation. Helical structures of semiflexible polymers are analyzed for several chain lengths under thermal conditions. Structural hyperphase diagrams, parametrized by torsion strength and temperature, are constructed and compared.
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spelling pubmed-64319262019-04-02 System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers Williams, Matthew J. Bachmann, Michael Polymers (Basel) Article Helical polymer bundles are an important fixture in biomolecular systems. The particular structural geometry of helix bundles is dependent on many factors including the length of the polymer chain. In this study, we performed Monte Carlo simulations of a coarse-grained model for helical polymers to determine the influence of polymer length on tertiary structure formation. Helical structures of semiflexible polymers are analyzed for several chain lengths under thermal conditions. Structural hyperphase diagrams, parametrized by torsion strength and temperature, are constructed and compared. MDPI 2016-06-27 /pmc/articles/PMC6431926/ /pubmed/30974521 http://dx.doi.org/10.3390/polym8070245 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Williams, Matthew J.
Bachmann, Michael
System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers
title System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers
title_full System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers
title_fullStr System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers
title_full_unstemmed System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers
title_short System-Size Dependence of Helix-Bundle Formation for Generic Semiflexible Polymers
title_sort system-size dependence of helix-bundle formation for generic semiflexible polymers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431926/
https://www.ncbi.nlm.nih.gov/pubmed/30974521
http://dx.doi.org/10.3390/polym8070245
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