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Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression

AIMS: Regional heterogeneities in contraction contribute to heart failure with reduced ejection fraction (HFrEF). We aimed to determine whether regional changes in myocardial relaxation similarly contribute to diastolic dysfunction in post-infarction HFrEF, and to elucidate the underlying mechanisms...

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Detalles Bibliográficos
Autores principales: Røe, Åsmund T, Ruud, Marianne, Espe, Emil K, Manfra, Ornella, Longobardi, Stefano, Aronsen, Jan M, Nordén, Einar Sjaastad, Husebye, Trygve, Kolstad, Terje R S, Cataliotti, Alessandro, Christensen, Geir, Sejersted, Ole M, Niederer, Steven A, Andersen, Geir Øystein, Sjaastad, Ivar, Louch, William E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432054/
https://www.ncbi.nlm.nih.gov/pubmed/30351410
http://dx.doi.org/10.1093/cvr/cvy257