Fischer rats exhibit maladaptive structural and molecular right ventricular remodelling in severe pulmonary hypertension: a genetically prone model for right heart failure

AIMS: The ability of the right ventricle (RV) to adapt to increased afterload is the major determinant of survival in patients with pulmonary hypertension (PH). In this study, we explored the effect of genetic background on RV adaptation and survival in a rat model of severe pulmonary arterial hyper...

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Detalles Bibliográficos
Autores principales: Suen, Colin M, Chaudhary, Ketul R, Deng, Yupu, Jiang, Baohua, Stewart, Duncan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432055/
https://www.ncbi.nlm.nih.gov/pubmed/30357319
http://dx.doi.org/10.1093/cvr/cvy258

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