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Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching
Topography and microstructure engineering are rapidly evolving areas of importance for biomedical and pharmaceutical remits. Here, PVA (Polyvinyl alcohol) microbubbles (diameter range ~126 to 414 μm) were used to fabricate beaded (beads-on) nanofibers using an electrohydrodynamic atomization (EHDA)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432371/ https://www.ncbi.nlm.nih.gov/pubmed/30970941 http://dx.doi.org/10.3390/polym9070265 |
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author | Yao, Zhi-Cheng Yuan, Qiantailang Ahmad, Zeeshan Huang, Jie Li, Jing-Song Chang, Ming-Wei |
author_facet | Yao, Zhi-Cheng Yuan, Qiantailang Ahmad, Zeeshan Huang, Jie Li, Jing-Song Chang, Ming-Wei |
author_sort | Yao, Zhi-Cheng |
collection | PubMed |
description | Topography and microstructure engineering are rapidly evolving areas of importance for biomedical and pharmaceutical remits. Here, PVA (Polyvinyl alcohol) microbubbles (diameter range ~126 to 414 μm) were used to fabricate beaded (beads-on) nanofibers using an electrohydrodynamic atomization (EHDA) technique. Mean fiber diameter, inter-bead distance, and aspect ratio (AR) were investigated by regulating EHDA process parameters. PVA fibers (diameter range ~233 to 737 nm) were obtained possessing bead ARs in the range of ~10 to 56%. AR was used to modulate hydrophilicity and active release. |
format | Online Article Text |
id | pubmed-6432371 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64323712019-04-02 Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching Yao, Zhi-Cheng Yuan, Qiantailang Ahmad, Zeeshan Huang, Jie Li, Jing-Song Chang, Ming-Wei Polymers (Basel) Communication Topography and microstructure engineering are rapidly evolving areas of importance for biomedical and pharmaceutical remits. Here, PVA (Polyvinyl alcohol) microbubbles (diameter range ~126 to 414 μm) were used to fabricate beaded (beads-on) nanofibers using an electrohydrodynamic atomization (EHDA) technique. Mean fiber diameter, inter-bead distance, and aspect ratio (AR) were investigated by regulating EHDA process parameters. PVA fibers (diameter range ~233 to 737 nm) were obtained possessing bead ARs in the range of ~10 to 56%. AR was used to modulate hydrophilicity and active release. MDPI 2017-07-03 /pmc/articles/PMC6432371/ /pubmed/30970941 http://dx.doi.org/10.3390/polym9070265 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Yao, Zhi-Cheng Yuan, Qiantailang Ahmad, Zeeshan Huang, Jie Li, Jing-Song Chang, Ming-Wei Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching |
title | Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching |
title_full | Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching |
title_fullStr | Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching |
title_full_unstemmed | Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching |
title_short | Controlled Morphing of Microbubbles to Beaded Nanofibers via Electrically Forced Thin Film Stretching |
title_sort | controlled morphing of microbubbles to beaded nanofibers via electrically forced thin film stretching |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432371/ https://www.ncbi.nlm.nih.gov/pubmed/30970941 http://dx.doi.org/10.3390/polym9070265 |
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