Cargando…

Synthetic biology approaches for improving photosynthesis

The phenomenal increase in agricultural yields that we have witnessed in the last century has slowed down as we approach the limits of selective breeding and optimization of cultivation techniques. To support the yield increase required to feed an ever-growing population, we will have to identify ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubis, Armin, Bar-Even, Arren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432428/
https://www.ncbi.nlm.nih.gov/pubmed/30715460
http://dx.doi.org/10.1093/jxb/erz029
_version_ 1783406132946010112
author Kubis, Armin
Bar-Even, Arren
author_facet Kubis, Armin
Bar-Even, Arren
author_sort Kubis, Armin
collection PubMed
description The phenomenal increase in agricultural yields that we have witnessed in the last century has slowed down as we approach the limits of selective breeding and optimization of cultivation techniques. To support the yield increase required to feed an ever-growing population, we will have to identify new ways to boost the efficiency with which plants convert light into biomass. This challenge could potentially be tackled using state-of-the-art synthetic biology techniques to rewrite plant carbon fixation. In this review, we use recent studies to discuss and demonstrate different approaches for enhancing carbon fixation, including engineering Rubisco for higher activity, specificity, and activation; changing the expression level of enzymes within the Calvin cycle to avoid kinetic bottlenecks; introducing carbon-concentrating mechanisms such as inorganic carbon transporters, carboxysomes, and C(4) metabolism; and rewiring photorespiration towards more energetically efficient routes or pathways that do not release CO(2). We conclude by noting the importance of prioritizing and combining different approaches towards continuous and sustainable increase of plant productivities.
format Online
Article
Text
id pubmed-6432428
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-64324282019-04-01 Synthetic biology approaches for improving photosynthesis Kubis, Armin Bar-Even, Arren J Exp Bot Expert Views The phenomenal increase in agricultural yields that we have witnessed in the last century has slowed down as we approach the limits of selective breeding and optimization of cultivation techniques. To support the yield increase required to feed an ever-growing population, we will have to identify new ways to boost the efficiency with which plants convert light into biomass. This challenge could potentially be tackled using state-of-the-art synthetic biology techniques to rewrite plant carbon fixation. In this review, we use recent studies to discuss and demonstrate different approaches for enhancing carbon fixation, including engineering Rubisco for higher activity, specificity, and activation; changing the expression level of enzymes within the Calvin cycle to avoid kinetic bottlenecks; introducing carbon-concentrating mechanisms such as inorganic carbon transporters, carboxysomes, and C(4) metabolism; and rewiring photorespiration towards more energetically efficient routes or pathways that do not release CO(2). We conclude by noting the importance of prioritizing and combining different approaches towards continuous and sustainable increase of plant productivities. Oxford University Press 2019-02-15 2019-01-31 /pmc/articles/PMC6432428/ /pubmed/30715460 http://dx.doi.org/10.1093/jxb/erz029 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Experimental Biology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Expert Views
Kubis, Armin
Bar-Even, Arren
Synthetic biology approaches for improving photosynthesis
title Synthetic biology approaches for improving photosynthesis
title_full Synthetic biology approaches for improving photosynthesis
title_fullStr Synthetic biology approaches for improving photosynthesis
title_full_unstemmed Synthetic biology approaches for improving photosynthesis
title_short Synthetic biology approaches for improving photosynthesis
title_sort synthetic biology approaches for improving photosynthesis
topic Expert Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432428/
https://www.ncbi.nlm.nih.gov/pubmed/30715460
http://dx.doi.org/10.1093/jxb/erz029
work_keys_str_mv AT kubisarmin syntheticbiologyapproachesforimprovingphotosynthesis
AT barevenarren syntheticbiologyapproachesforimprovingphotosynthesis