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Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells
Spontaneous cell movement is underpinned by an asymmetric distribution of signaling molecules including small G proteins and phosphoinositides on the cell membrane. However, the molecular network necessary for spontaneous symmetry breaking has not been fully elucidated. Here, we report that, in Dict...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432713/ https://www.ncbi.nlm.nih.gov/pubmed/30745337 http://dx.doi.org/10.1242/jcs.224121 |