Modular systems metabolic engineering enables balancing of relevant pathways for l-histidine production with Corynebacterium glutamicum

BACKGROUND: l-Histidine biosynthesis is embedded in an intertwined metabolic network which renders microbial overproduction of this amino acid challenging. This is reflected in the few available examples of histidine producers in literature. Since knowledge about the metabolic interplay is limited,...

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Detalles Bibliográficos
Autores principales: Schwentner, Andreas, Feith, André, Münch, Eugenia, Stiefelmaier, Judith, Lauer, Ira, Favilli, Lorenzo, Massner, Christoph, Öhrlein, Johannes, Grund, Bastian, Hüser, Andrea, Takors, Ralf, Blombach, Bastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432763/
https://www.ncbi.nlm.nih.gov/pubmed/30962820
http://dx.doi.org/10.1186/s13068-019-1410-2

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