Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans

We assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compa...

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Detalles Bibliográficos
Autores principales: Mansuy, Jean-Michel, El Costa, Hicham, Gouilly, Jordi, Mengelle, Catherine, Pasquier, Christophe, Martin-Blondel, Guillaume, Izopet, Jacques, Jabrane-Ferrat, Nabila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433016/
https://www.ncbi.nlm.nih.gov/pubmed/30882325
http://dx.doi.org/10.3201/eid2504.171886
Descripción
Sumario:We assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compartmentalized in the male reproductive tract.

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