Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans

We assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compa...

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Autores principales: Mansuy, Jean-Michel, El Costa, Hicham, Gouilly, Jordi, Mengelle, Catherine, Pasquier, Christophe, Martin-Blondel, Guillaume, Izopet, Jacques, Jabrane-Ferrat, Nabila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433016/
https://www.ncbi.nlm.nih.gov/pubmed/30882325
http://dx.doi.org/10.3201/eid2504.171886
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author Mansuy, Jean-Michel
El Costa, Hicham
Gouilly, Jordi
Mengelle, Catherine
Pasquier, Christophe
Martin-Blondel, Guillaume
Izopet, Jacques
Jabrane-Ferrat, Nabila
author_facet Mansuy, Jean-Michel
El Costa, Hicham
Gouilly, Jordi
Mengelle, Catherine
Pasquier, Christophe
Martin-Blondel, Guillaume
Izopet, Jacques
Jabrane-Ferrat, Nabila
author_sort Mansuy, Jean-Michel
collection PubMed
description We assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compartmentalized in the male reproductive tract.
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spelling pubmed-64330162019-04-03 Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans Mansuy, Jean-Michel El Costa, Hicham Gouilly, Jordi Mengelle, Catherine Pasquier, Christophe Martin-Blondel, Guillaume Izopet, Jacques Jabrane-Ferrat, Nabila Emerg Infect Dis Research Letter We assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compartmentalized in the male reproductive tract. Centers for Disease Control and Prevention 2019-04 /pmc/articles/PMC6433016/ /pubmed/30882325 http://dx.doi.org/10.3201/eid2504.171886 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Mansuy, Jean-Michel
El Costa, Hicham
Gouilly, Jordi
Mengelle, Catherine
Pasquier, Christophe
Martin-Blondel, Guillaume
Izopet, Jacques
Jabrane-Ferrat, Nabila
Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_full Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_fullStr Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_full_unstemmed Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_short Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_sort peripheral plasma and semen cytokine response to zika virus in humans
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433016/
https://www.ncbi.nlm.nih.gov/pubmed/30882325
http://dx.doi.org/10.3201/eid2504.171886
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