Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

We identified an influenza B isolate harboring a Gly407Ser neuraminidase substitution in an immunocompromised patient in Canada before antiviral therapy. This mutation mediated reduced susceptibility to oseltamivir, zanamivir, and peramivir, most likely by preventing interaction with the catalytic A...

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Detalles Bibliográficos
Autores principales: Abed, Yacine, Fage, Clément, Lagüe, Patrick, Carbonneau, Julie, Papenburg, Jesse, Vinh, Donald C., Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433030/
https://www.ncbi.nlm.nih.gov/pubmed/30882323
http://dx.doi.org/10.3201/eid2504.181554

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