Cargando…
A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2
The MEF2 family of transcription factors restricts excitatory synapse number in an activity-dependent fashion during development, yet MEF2 has not been implicated in long-term synaptic depression (LTD), which is thought to initiate synapse elimination. Mutations in MEF2 pathways are implicated in au...
Autores principales: | Andzelm, Milena M., Vanness, Devorah, Greenberg, Michael E., Linden, David J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433166/ https://www.ncbi.nlm.nih.gov/pubmed/30699340 http://dx.doi.org/10.1016/j.celrep.2019.01.004 |
Ejemplares similares
-
Synaptic aging disrupts synaptic morphology and function in cerebellar Purkinje cells
por: Fan, Wen-Juan, et al.
Publicado: (2018) -
Modeling mGluR1 mediated synaptic depression in cerebellar Purkinje cells
por: Su, Yizhen, et al.
Publicado: (2014) -
Protein tyrosine phosphatase receptor type R is required for Purkinje cell responsiveness in cerebellar long-term depression
por: Erkens, Mirthe, et al.
Publicado: (2015) -
HCN1 channels in cerebellar Purkinje cells promote late stages of learning and constrain synaptic inhibition
por: Rinaldi, Arianna, et al.
Publicado: (2013) -
Intravenous Anesthetic, Propofol Affects Synaptic Responses in Cerebellar Purkinje Cells
por: Lee, Kwan Young, et al.
Publicado: (2018)