Cargando…

A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2

The MEF2 family of transcription factors restricts excitatory synapse number in an activity-dependent fashion during development, yet MEF2 has not been implicated in long-term synaptic depression (LTD), which is thought to initiate synapse elimination. Mutations in MEF2 pathways are implicated in au...

Descripción completa

Detalles Bibliográficos
Autores principales: Andzelm, Milena M., Vanness, Devorah, Greenberg, Michael E., Linden, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433166/
https://www.ncbi.nlm.nih.gov/pubmed/30699340
http://dx.doi.org/10.1016/j.celrep.2019.01.004

Ejemplares similares