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A pilot study showing that repeated exposure to stress produces alterations in subsequent responses to anesthetics in rats

The repeated use of a drug frequently leads to alterations in the response to that drug. We undertook this study to determine whether multiple exposures to the general anesthetic produced alterations in subsequent exposures to this anesthetic. For this study, adult male rats were anesthetized with 2...

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Detalles Bibliográficos
Autores principales: Wang, Lingzhi, Holland, Lindsay, Fong, Robert, Khokhar, Suhail, Fox, Aaron P., Xie, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433219/
https://www.ncbi.nlm.nih.gov/pubmed/30908509
http://dx.doi.org/10.1371/journal.pone.0214093