Oral activity of the antimalarial endoperoxide 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) against Leishmania donovani complex

Visceral leishmaniasis (VL) is a major problem worldwide and causes significant morbidity and mortality. Existing drugs against VL have limitations, including their invasive means of administration long duration of treatment regimens. There are also concerns regarding increasing treatment relapses a...

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Detalles Bibliográficos
Autores principales: Kwofie, Kofi Dadzie, Sato, Kai, Sanjoba, Chizu, Hino, Akina, Shimogawara, Rieko, Amoa-Bosompem, Michael, Ayi, Irene, Boakye, Daniel A., Anang, Abraham K., Chang, Kyung-Soo, Ohashi, Mitsuko, Kim, Hye-Sook, Ohta, Nobuo, Matsumoto, Yoshitsugu, Iwanaga, Shiroh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433226/
https://www.ncbi.nlm.nih.gov/pubmed/30908481
http://dx.doi.org/10.1371/journal.pntd.0007235

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