Combining anti-IL-7Rα antibodies with autoantigen-specific immunotherapy enhances non-specific cytokine production but fails to prevent Type 1 Diabetes

Autoantigen-specific methods to prevent and treat Type 1 Diabetes (T1D) carry high hopes to permanently cure this disease, but have largely failed in clinical trials. One suggested approach to increase the efficacy of islet antigen-specific vaccination is to combine it with a modulator of the T cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Vazquez-Mateo, Cristina, Collins, Justin, Goldberg, Sarah J., Lawson, Maxx, Hernandez-Escalante, Jaileene, Dooms, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433345/
https://www.ncbi.nlm.nih.gov/pubmed/30908554
http://dx.doi.org/10.1371/journal.pone.0214379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433345/
https://www.ncbi.nlm.nih.gov/pubmed/30908554
http://dx.doi.org/10.1371/journal.pone.0214379

Ejemplares similares