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Biophysical mechanisms in the mammalian respiratory oscillator re-examined with a new data-driven computational model
An autorhythmic population of excitatory neurons in the brainstem pre-Bötzinger complex is a critical component of the mammalian respiratory oscillator. Two intrinsic neuronal biophysical mechanisms—a persistent sodium current ([Formula: see text]) and a calcium-activated non-selective cationic curr...
Autores principales: | Phillips, Ryan S, John, Tibin T, Koizumi, Hidehiko, Molkov, Yaroslav I, Smith, Jeffrey C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433470/ https://www.ncbi.nlm.nih.gov/pubmed/30907727 http://dx.doi.org/10.7554/eLife.41555 |
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