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Enhanced efficacy of histone deacetylase inhibitor panobinostat combined with dual PI3K/mTOR inhibitor BEZ235 against glioblastoma
Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. Despite multiple treatment strategies, the prognosis is still poor. This study aimed to evaluate the efficacy of combination treatment of GBM with the histone deacetylase (HDAC) inhibitor panobinostat and dual phosphoi...
Autores principales: | Meng, Wei, Wang, Baocheng, Mao, Weiwei, Wang, Jiajia, Zhao, Yang, Li, Qifeng, Zhang, Chenran, Ma, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nagoya University
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433629/ https://www.ncbi.nlm.nih.gov/pubmed/30962658 http://dx.doi.org/10.18999/nagjms.81.1.93 |
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