Metformin and tenovin‐6 synergistically induces apoptosis through LKB1‐independent SIRT1 down‐regulation in non‐small cell lung cancer cells

Sirtuin 1 (SIRT1) is known to play a role in a variety of tumorigenesis processes by deacetylating histone and non‐histone proteins; however, antitumour effects by suppressing SIRT1 activity in non‐small cell lung cancer (NSCLC) remain unclear. This study was designed to scrutinize clinicopathologic...

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Detalles Bibliográficos
Autores principales: Lee, Bo Bin, Kim, Yujin, Kim, Dongho, Cho, Eun Yoon, Han, Joungho, Kim, Hong Kwan, Shim, Young Mog, Kim, Duk‐Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433689/
https://www.ncbi.nlm.nih.gov/pubmed/30710424
http://dx.doi.org/10.1111/jcmm.14194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433689/
https://www.ncbi.nlm.nih.gov/pubmed/30710424
http://dx.doi.org/10.1111/jcmm.14194

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