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O‐GlcNAc transferase activates stem‐like cell potential in hepatocarcinoma through O‐GlcNAcylation of eukaryotic initiation factor 4E

O‐GlcNAcylation catalysed by O‐GlcNAc transferase (OGT) is a reversible post‐translational modification. O‐GlcNAcylation participates in transcription, epigenetic regulation, and intracellular signalling. Dysregulation of O‐GlcNAcylation in response to high glucose or OGT expression has been implica...

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Detalles Bibliográficos
Autores principales: Cao, Benjin, Duan, Meng, Xing, Yang, Liu, Chanjuan, Yang, Fan, Li, Yinan, Yang, Tianxiao, Wei, Yuanyan, Gao, Qiang, Jiang, Jianhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433694/
https://www.ncbi.nlm.nih.gov/pubmed/30677218
http://dx.doi.org/10.1111/jcmm.14043