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Matrine attenuates high‐fat diet‐induced in vivo and ox‐LDL‐induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways

Lipid metabolism disorders lead to vascular endothelial injury. Matrine is an alkaloid that has been used to improve obesity and diabetes and for the treatment of hepatitis B. However, its effect on lipid metabolism disorders and vascular injury is unclear. Here, we investigated the effect of matrin...

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Detalles Bibliográficos
Autores principales: Zhang, Song, Guo, Shun, Gao, Xiao‐bo, Liu, An, Jiang, Wei, Chen, Xi, Yang, Peng, Liu, Lin‐na, Shi, Lei, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433715/
https://www.ncbi.nlm.nih.gov/pubmed/30770623
http://dx.doi.org/10.1111/jcmm.14180