Absence of PARP‐1 affects Cxcl12 expression by increasing DNA demethylation

Poly [ADP‐ribose] polymerase 1 (PARP‐1) has an inhibitory effect on C‐X‐C motif chemokine 12 gene (Cxcl12) transcription. We examined whether PARP‐1 affects the epigenetic control of Cxcl12 expression by changing its DNA methylation pattern. We observed increased expression of Cxcl12 in PARP‐1 knock...

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Detalles Bibliográficos
Autores principales: Tolić, Anja, Grdović, Nevena, Dinić, Svetlana, Rajić, Jovana, Đorđević, Miloš, Sinadinović, Marija, Arambašić Jovanović, Jelena, Mihailović, Mirjana, Poznanović, Goran, Uskoković, Aleksandra, Vidaković, Melita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433732/
https://www.ncbi.nlm.nih.gov/pubmed/30697918
http://dx.doi.org/10.1111/jcmm.14154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433732/
https://www.ncbi.nlm.nih.gov/pubmed/30697918
http://dx.doi.org/10.1111/jcmm.14154

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