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Absence of PARP‐1 affects Cxcl12 expression by increasing DNA demethylation
Poly [ADP‐ribose] polymerase 1 (PARP‐1) has an inhibitory effect on C‐X‐C motif chemokine 12 gene (Cxcl12) transcription. We examined whether PARP‐1 affects the epigenetic control of Cxcl12 expression by changing its DNA methylation pattern. We observed increased expression of Cxcl12 in PARP‐1 knock...
Autores principales: | Tolić, Anja, Grdović, Nevena, Dinić, Svetlana, Rajić, Jovana, Đorđević, Miloš, Sinadinović, Marija, Arambašić Jovanović, Jelena, Mihailović, Mirjana, Poznanović, Goran, Uskoković, Aleksandra, Vidaković, Melita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433732/ https://www.ncbi.nlm.nih.gov/pubmed/30697918 http://dx.doi.org/10.1111/jcmm.14154 |
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