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Tracking a Fast-Moving Disease: Longitudinal Markers, Monitoring, and Clinical Trial Endpoints in ALS

Amyotrophic lateral sclerosis (ALS) encompasses a heterogeneous group of phenotypes with different progression rates, varying degree of extra-motor involvement and divergent progression patterns. The natural history of ALS is increasingly evaluated by large, multi-time point longitudinal studies, ma...

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Detalles Bibliográficos
Autores principales:	Chipika, Rangariroyashe Hannah, Finegan, Eoin, Li Hi Shing, Stacey, Hardiman, Orla, Bede, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433752/ https://www.ncbi.nlm.nih.gov/pubmed/30941088 http://dx.doi.org/10.3389/fneur.2019.00229

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