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Radiochemotherapy combined with NK cell transfer followed by second-line PD-1 inhibition in a patient with NSCLC stage IIIb inducing long-term tumor control: a case study

BACKGROUND: Membrane heat shock protein 70 (mHsp70) is indicative of high-risk tumors and serves as a tumor-specific target for natural killer (NK) cells stimulated with Hsp70 peptide (TKD) and Interleukin(IL)-2. Radiochemotherapy (RCT), mHsp70-targeting NK cells, and programmed death(PD)-1 inhibiti...

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Detalles Bibliográficos
Autores principales: Kokowski, Konrad, Stangl, Stefan, Seier, Sophie, Hildebrandt, Martin, Vaupel, Peter, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433810/
https://www.ncbi.nlm.nih.gov/pubmed/30747241
http://dx.doi.org/10.1007/s00066-019-01434-9