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The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)(2)D(3) Induces Super-Enhancers Bound by VDR

A super-enhancer (SE) is a cluster of enhancers with a relatively high density of particular chromatin features. SEs typically regulate key genes that can determine cell identity and differentiation. Identifying SEs and their effects may be critical in predicting key regulatory genes, such as master...

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Detalles Bibliográficos
Autores principales: Lu, Ming, McComish, Bennet J., Burdon, Kathryn P., Taylor, Bruce V., Körner, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433938/
https://www.ncbi.nlm.nih.gov/pubmed/30941131
http://dx.doi.org/10.3389/fimmu.2019.00488

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