Cargando…

A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells

Long noncoding RNAs (lncRNAs) have emerged as important components of gene regulatory network in embryonic stem cells (ESCs). However, the function and molecular mechanism of lncRNAs are still largely unknown. Here we identifies Trincr1 (TRIM71 interacting long noncoding RNA 1) lncRNA that regulates...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ya-Pu, Duan, Fei-Fei, Zhao, Yu-Ting, Gu, Kai-Li, Liao, Le-Qi, Su, Huai-Bin, Hao, Jing, Zhang, Kun, Yang, Na, Wang, Yangming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433952/ https://www.ncbi.nlm.nih.gov/pubmed/30911006 http://dx.doi.org/10.1038/s41467-019-08911-w

Ejemplares similares

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation
por: Chang, Hao-Ming, et al.
Publicado: (2012)

The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1
por: Welte, Thomas, et al.
Publicado: (2019)

Post-transcriptional repression of CFP-1 expands the regulatory repertoire of LIN-41/TRIM71
por: Kumari, Pooja, et al.
Publicado: (2023)

Both ERK1 and ERK2 Are Required for Enterovirus 71 (EV71) Efficient Replication
por: Zhu, Meng, et al.
Publicado: (2015)

Intermittent ERK oscillations downstream of FGF in mouse embryonic stem cells
por: Raina, Dhruv, et al.
Publicado: (2022)

Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs
por: Liu, Qiuying, et al.
Publicado: (2021)

TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells
por: Rowe, Helen M., et al.
Publicado: (2013)

Gain-of-function mutations in Trim71 linked to congenital hydrocephalus
por: Chen, Yingying, et al.
Publicado: (2023)

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function
por: Loedige, Inga, et al.
Publicado: (2013)

RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1
por: Hasan, Md Rakibul, et al.
Publicado: (2020)

Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53
por: Chen, Yajie, et al.
Publicado: (2019)

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate
Publicado: (1992)

The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall
por: Boylan, Michael, et al.
Publicado: (2020)

ERK inhibition represses gefitinib resistance in non-small cell lung cancer cells
por: Qi, Mengfan, et al.
Publicado: (2018)

The Long Noncoding RNA ZFAS1 Potentiates the Development of Hepatocellular Carcinoma via the microRNA-624/MDK/ERK/JNK/P38 Signaling Pathway
por: Duan, Rui, et al.
Publicado: (2020)

Trim24 and Trim33 Play a Role in Epigenetic Silencing of Retroviruses in Embryonic Stem Cells
por: Margalit, Liad, et al.
Publicado: (2020)

Enterovirus 71 induces degradation of TRIM38, a potential E3 ubiquitin ligase
por: Liu, Xinlei, et al.
Publicado: (2011)

Brain-wide identification of LIN-41 (TRIM71) protein-expressing neurons by NeuroPAL
por: Shih, Mushaine, et al.
Publicado: (2021)

Long noncoding RNA FGF14-AS2 inhibits breast cancer metastasis by regulating the miR-370-3p/FGF14 axis
por: Jin, Yucui, et al.
Publicado: (2020)

TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells
por: Fasching, Liana, et al.
Publicado: (2014)

FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7
por: Bai, Yu-Pan, et al.
Publicado: (2015)

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
por: Yuan, Jingsheng, et al.
Publicado: (2022)

Berberine inhibits enterovirus 71 replication by downregulating the MEK/ERK signaling pathway and autophagy
por: Wang, Huiqiang, et al.
Publicado: (2017)

Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain
por: Cuevas, Elisa, et al.
Publicado: (2015)

MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells
por: Shi, Weifeng, et al.
Publicado: (2014)

Long noncoding RNA DLGAP1-AS2 promotes tumorigenesis and metastasis by regulating the Trim21/ELOA/LHPP axis in colorectal cancer
por: Wang, Xue, et al.
Publicado: (2022)

The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes
por: Robbez-Masson, Luisa, et al.
Publicado: (2018)

TRIM21–SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis
por: Zhang, Panpan, et al.
Publicado: (2020)

Hepatic Fgf21 Expression Is Repressed after Simvastatin Treatment in Mice
por: Ziros, Panos, et al.
Publicado: (2016)

Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71
por: Mitschka, Sibylle, et al.
Publicado: (2015)

TRIM71 suppresses tumorigenesis via modulation of Lin28B-let-7-HMGA2 signaling
por: Yin, Jinlong, et al.
Publicado: (2016)

TRIM71 Deficiency Causes Germ Cell Loss During Mouse Embryogenesis and Is Associated With Human Male Infertility
por: Torres-Fernández, Lucia A., et al.
Publicado: (2021)

Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of enterovirus 71
por: Wong, Wen-Rou, et al.
Publicado: (2005)

Loss of maternal Trim28 causes male-predominant early embryonic lethality
por: Sampath Kumar, Abhishek, et al.
Publicado: (2017)

Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development
por: Su, Xiaomin, et al.
Publicado: (2018)

Microtubular TRIM36 E3 Ubiquitin Ligase in Embryonic Development and Spermatogenesis
por: Mascaro, Martina, et al.
Publicado: (2022)

Xiaozheng pill exerts an anti-mammary hyperplasia effect through Raf/ERK/ELK and HIF-1α/bFGF pathways
por: Liu, Yu-fei, et al.
Publicado: (2023)

TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L
por: Wong, Derek, et al.
Publicado: (2020)

TRIM15 and CYLD regulate ERK activation via lysine 63-linked polyubiquitination
por: Zhu, Guixin, et al.
Publicado: (2021)

ZHX3 promotes the progression of urothelial carcinoma of the bladder via repressing of RGS2 and is a novel substrate of TRIM21
por: Deng, Minhua, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7m974afd7jsat9b8d8vh57c3mj