Phase 1 Study Evaluating the Association of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib and Cetuximab in Recurrent/Metastatic p16-Negative Squamous Cell Carcinoma of the Head and Neck

Background: The majority of human papillomavirus (HPV)-negative squamous cell carcinoma of the head and neck (SCCHN) present upregulation of the epidermal growth factor receptor (EGFR) and frequent alterations in the cyclin D1-cyclin dependent kinase (CDK) 4/6 (CDK 4/6)-retinoblastoma protein (pRb)...

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Chi tiết về thư mục
Những tác giả chính: Seront, Emmanuel, Schmitz, Sandra, Papier, Matthias, van Maanen, Aline, Henry, Stéphanie, Lonchay, Christophe, Rottey, Sylvie, van Caloen, Gabrielle, Machiels, Jean-Pascal
Định dạng: Online Bài viết Texto
Ngôn ngữ:English
Được phát hành: Frontiers Media S.A. 2019
Những chủ đề:
Oncology
Truy cập trực tuyến:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433958/
https://www.ncbi.nlm.nih.gov/pubmed/30941307
http://dx.doi.org/10.3389/fonc.2019.00155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433958/
https://www.ncbi.nlm.nih.gov/pubmed/30941307
http://dx.doi.org/10.3389/fonc.2019.00155

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