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Investigating the Connection Between Endogenous Heme Accumulation and COX2 Activity in Cancer Cells
Heme, an iron-containing porphyrin, is fundamental for a variety of functions in cell homeostasis. Nevertheless, recent data indicate that dysregulation of heme metabolism might promote tumorigenesis. The intracellular heme pool is finely regulated through the control of heme synthesis, degradation,...
Autores principales: | Destefanis, Francesca, Fiorito, Veronica, Altruda, Fiorella, Tolosano, Emanuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433962/ https://www.ncbi.nlm.nih.gov/pubmed/30941311 http://dx.doi.org/10.3389/fonc.2019.00162 |
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