Sub-Acute Oral Toxicity of a Novel Derivative of Agomelatine in Rats in a Sex-Dependent Manner

Agomelatine (AGO) is a new type of antidepressant with demonstrated antidepressant effects and a unique modulating circadian rhythm action. However, AGO has hepatotoxicity, which limits its clinical application. In order to develop new drugs that cause less liver injury than AGO, a series of derivat...

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Detalles Bibliográficos
Autores principales: Yang, Qiushi, Zhou, Xuelin, Li, Jingyi, Ma, Yi, Lu, Li, Xiong, Jie, Xu, Pingxiang, Li, Yuhang, Chen, Yi, Gu, Wei, Xue, Ming, Jin, Zengliang, Li, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433965/
https://www.ncbi.nlm.nih.gov/pubmed/30941037
http://dx.doi.org/10.3389/fphar.2019.00242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433965/
https://www.ncbi.nlm.nih.gov/pubmed/30941037
http://dx.doi.org/10.3389/fphar.2019.00242

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