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CXCR6(+) NK Cells in Human Fetal Liver and Spleen Possess Unique Phenotypic and Functional Capabilities

Tissue-resident Natural Killer (NK) cells vary in phenotype according to tissue origin, but are typically CD56(bright), CXCR6(+), and CD69(+). NK cells appear very early in fetal development, but little is known about when markers of tissue residency appear during gestation and whether the expressio...

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Detalles Bibliográficos
Autores principales: Angelo, Laura S., Bimler, Lynn H., Nikzad, Rana, Aviles-Padilla, Kevin, Paust, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433986/
https://www.ncbi.nlm.nih.gov/pubmed/30941128
http://dx.doi.org/10.3389/fimmu.2019.00469