Connectivity map identifies luteolin as a treatment option of ischemic stroke by inhibiting MMP9 and activation of the PI3K/Akt signaling pathway

This study aimed to explore potential new drugs in the treatment of ischemic stroke by Connectivity Map (CMap) and to determine the role of luteolin on ischemic stroke according to its effects on matrix metalloproteinase-9 (MMP9) and PI3K/Akt signaling pathway. Based on published gene expression dat...

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Detalles Bibliográficos
Autores principales: Luo, Shijian, Li, Huiqing, Mo, Zhihuai, Lei, Junjie, Zhu, Lingjuan, Huang, Yanxia, Fu, Ruying, Li, Chunyi, Huang, Yihuan, Liu, Kejia, Chen, Wenli, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434019/
https://www.ncbi.nlm.nih.gov/pubmed/30911000
http://dx.doi.org/10.1038/s12276-019-0229-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434019/
https://www.ncbi.nlm.nih.gov/pubmed/30911000
http://dx.doi.org/10.1038/s12276-019-0229-z

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