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LMP1 and 2A Induce the Expression of Nrf2 Through Akt Signaling Pathway in Epstein-Barr Virus–Transformed B Cells

The transcription factor Nrf2, which regulates the expression of antioxidant and cytoprotective enzymes, contributes to cell proliferation and resistance to chemotherapy. Nrf2 is also dysregulated in many cancers such as lung, head and neck, and breast cancers, but its role in Epstein-Barr virus (EB...

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Detalles Bibliográficos
Autores principales: Yun, Sun-mi, Kim, Yeong Seok, Hur, Dae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434054/
https://www.ncbi.nlm.nih.gov/pubmed/30909091
http://dx.doi.org/10.1016/j.tranon.2019.02.009