Skeletal muscle Nur77 and NOR1 insulin responsiveness is blunted in obesity and type 2 diabetes but improved after exercise training

Obesity and type 2 diabetes (T2DM) are characterized by a blunted metabolic response to insulin, and strongly manifests in skeletal muscle insulin resistance. The orphan nuclear receptors, Nur77 and NOR1, regulate insulin‐stimulated nutrient metabolism where Nur77 and NOR1 gene expression is increas...

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Detalles Bibliográficos
Autores principales: Mey, Jacob T., Solomon, Thomas P. J., Kirwan, John P., Haus, Jacob M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434071/
https://www.ncbi.nlm.nih.gov/pubmed/30912283
http://dx.doi.org/10.14814/phy2.14042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434071/
https://www.ncbi.nlm.nih.gov/pubmed/30912283
http://dx.doi.org/10.14814/phy2.14042

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