Cargando…

The exon junction complex senses energetic stress and regulates contractility and cell architecture in cardiac myocytes

The exon junction complex (EJC) is the main mechanism by which cells select specific mRNAs for translation into protein. We hypothesized that the EJC is involved in the regulation of gene expression during the stress response in cardiac myocytes, with implications for the failing heart. In cultured...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pierrat, Olivier A., Paudyal, Anju, Woodruff, James, Koroleva, Olga, Boateng, Samuel Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434082/ https://www.ncbi.nlm.nih.gov/pubmed/28566540 http://dx.doi.org/10.1042/BSR20170707

Ejemplares similares

Linking metabolic and contractile dysfunction in aged cardiac myocytes
por: Barton, Gregory P., et al.
Publicado: (2017)

Calcium Signaling and Contractility in Cardiac Myocyte of Wolframin Deficient Rats
por: Cagalinec, Michal, et al.
Publicado: (2019)

Reversible and Irreversible Effects of Electroporation on Contractility and Calcium Homeostasis in Isolated Cardiac Ventricular Myocytes
por: Chaigne, Sébastien, et al.
Publicado: (2022)

Image Processing Techniques for Assessing Contractility in Isolated Neonatal Cardiac Myocytes
por: Bazan, Carlos, et al.
Publicado: (2011)

Image Processing Techniques for Assessing Contractility in Isolated Adult Cardiac Myocytes
por: Bazan, Carlos, et al.
Publicado: (2009)

Editorial: Cardiac Microvascular Endothelium Contribution to Cardiac Myocyte Growth, Structure, and Contractile Function
por: Altara, Raffaele, et al.
Publicado: (2019)

The interaction of electrically stimulated twitches and spontaneous contractile waves in single cardiac myocytes
Publicado: (1986)

Effects of contractile protein phosphorylation on force development in permeabilized rat cardiac myocytes
por: Verduyn, S. C., et al.
Publicado: (2007)

Intron exon boundary junctions in human genome have in-built unique structural and energetic signals
por: Mishra, Akhilesh, et al.
Publicado: (2021)

Contractile activity and cell-cell contact regulate myofibrillar organization in cultured cardiac myocytes
Publicado: (1993)

Primary role of sarcoplasmic reticulum in phasic contractile activation of cardiac myocytes with shunted myolemma
Publicado: (1981)

Agonist Activated PKCβ(II) Translocation and Modulation of Cardiac Myocyte Contractile Function
por: Hwang, Hyosook, et al.
Publicado: (2013)

Glucocorticoid stimulation increases cardiac contractility by SGK1-dependent SOCE-activation in rat cardiac myocytes
por: Wester, Michael, et al.
Publicado: (2019)

Direct, Differential Effects of Tamoxifen, 4-Hydroxytamoxifen, and Raloxifene on Cardiac Myocyte Contractility and Calcium Handling
por: Asp, Michelle L., et al.
Publicado: (2013)

Riociguat and cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats
por: Reinke, Yvonne, et al.
Publicado: (2015)

Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation
por: Biermann, Daniel, et al.
Publicado: (2016)

Early changes in myocyte contractility and cardiac function in streptozotocin-induced type 1 diabetes in rats
por: Marchini, Gustavo S., et al.
Publicado: (2020)

Evolution of Flight Muscle Contractility and Energetic Efficiency
por: Cao, Tianxin, et al.
Publicado: (2020)

Stretch-induced increase in cardiac contractility is independent of myocyte Ca(2+) while block of stretch channels by streptomycin improves contractility after ischemic stunning
por: Rhodes, Samhita S, et al.
Publicado: (2015)

JuncDB: an exon–exon junction database
por: Chorev, Michal, et al.
Publicado: (2016)

Energetics Equivalent of the Cardiac Force-Length End-Systolic Zone: Implications for Contractility and Economy of Contraction
por: Tran, Kenneth, et al.
Publicado: (2020)

KChIP2 regulates the cardiac Ca(2+) transient and myocyte contractility by targeting ryanodine receptor activity
por: Nassal, Drew M., et al.
Publicado: (2017)

Cardiac myocyte intrinsic contractility and calcium handling deficits underlie heart organ dysfunction in murine cancer cachexia
por: Law, Michelle L., et al.
Publicado: (2021)

Novel Small-Molecule Troponin Activator Increases Cardiac Contractile Function Without Negative Impact on Energetics
por: He, Huamei, et al.
Publicado: (2021)

Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture
por: Manalo, Annabelle, et al.
Publicado: (2018)

Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts
por: Menges, Lukas, et al.
Publicado: (2019)

Stem cells can form gap junctions with cardiac myocytes and exert pro-arrhythmic effects
por: Smit, Nicoline W., et al.
Publicado: (2014)

The Dysferlin Transcript Containing the Alternative Exon 40a is Essential for Myocyte Functions
por: Ballouhey, Océane, et al.
Publicado: (2021)

Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues
por: Ravenscroft, Stephanie M., et al.
Publicado: (2016)

Wnt5a-YAP signaling axis mediates mechanotransduction in cardiac myocytes and contributes to contractile dysfunction induced by pressure overload
por: Kishimoto, Hiroshi, et al.
Publicado: (2023)

Effects of omecamtiv mecarbil on calcium‐transients and contractility in a translational canine myocyte model
por: Gao, BaoXi, et al.
Publicado: (2020)

Redox signaling in cardiac myocytes
por: Santos, Celio X.C., et al.
Publicado: (2011)

Heterocellular communication in the heart: electron tomography of telocyte–myocyte junctions
por: Gherghiceanu, Mihaela, et al.
Publicado: (2011)

Single adult rabbit and rat cardiac myocytes retain the Ca2+- and species-dependent systolic and diastolic contractile properties of intact muscle
Publicado: (1986)

Glucose-6-Phosphate Dehydrogenase and NADPH Redox Regulates Cardiac Myocyte L-Type Calcium Channel Activity and Myocardial Contractile Function
por: Rawat, Dhwajbahadur K., et al.
Publicado: (2012)

Highly variable contractile performance correlates with myocyte content in trabeculae from failing human hearts
por: Munro, Michelle L., et al.
Publicado: (2018)

Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays
por: Kechris, Katerina, et al.
Publicado: (2008)

Energetics and structure of grain boundary triple junctions in graphene
por: Hirvonen, Petri, et al.
Publicado: (2017)

The pacemaker current in cardiac Purkinje myocytes
Publicado: (1995)

Epigenetic regulation of cardiac myocyte differentiation(†)
por: Oyama, Kyohei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qd3k2s9a9jnv07bpru4p2tgcrm