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Inhibition of miR-143 during ischemia cerebral injury protects neurones through recovery of the hexokinase 2-mediated glucose uptake

Ischemic stroke, a major cause of death, is caused by occlusion of a blood vessel, resulting in significant reduction in regional cerebral blood flow. MiRNAs are a family of short noncoding RNAs (18–22 nts) and bind the 3′-UTR of their target genes to suppress the gene expression post-transcriptiona...

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Detalles Bibliográficos
Autores principales: Zeng, Xianzhu, Liu, Na, Zhang, Jing, Wang, Lei, Zhang, Zhecheng, Zhu, Ju, Li, Qian, Wang, Yuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434090/
https://www.ncbi.nlm.nih.gov/pubmed/28522551
http://dx.doi.org/10.1042/BSR20170216